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Propecia propecia sides is a once-a-day pill treatment for male-pattern hair loss, or androgenetic alopecia. Male-pattern hair loss is when the hairline recedes and propecia sides hair thins at the temples and crown. This condition is hereditary and affects close to 50 percent of the male population aged 50 years or older. It is sometimes recognized propecia sides by a horseshoe-shaped fringe around the sides and the back of the head. Propecias effects on hair loss were actually discovered by accident. Originally marketed as propecia sides Proscar, doctors first prescribed 5 mg of finasteride (the active ingredient in Propecia) to treat benign prostatic hyperplasia (BPH more commonly known as an enlarged prostate gland. Merck later stumbled upon a remarkable side effect of Proscar treatment: some balding patients started to grow hair back. By dropping the dose of finasteride to 1 mg, researchers found a way to correct male-pattern hair loss. In 1997, Merck introduced Propecia as a new use for finasteride. The company had developed the synthetic compound five years earlier. With nearly half a billion dollars of research behind it, Propecia entered the drug market to high acclaim. After its first year, about 400,000 men in the.S. Were filling prescriptions for Propecia and taking the drug daily. Merck provided early Propecia users propecia sides with a list of sexual side effects researchers had uncovered in clinical trials. However, it later came to light that the company wasnt telling the whole story. Upon approval of the drug, Merck disclosed that.8 percent of Propecia patients had one or more adverse sexual experiences, compared with.1 percent of patients taking a placebo. The company failed to warn, however, that these problems can persist even after patients stop taking the drug. In fact, Merck originally claimed that all of these issues would resolve after discontinuation of the drug. Food and Drug Administration (FDA) has since required updates to the drugs label to reflect the potential for persistent sexual side effects with Propecia use. Thousands of men have sued Merck over allegations that the drug maker failed to provide adequate warnings and even knowingly and recklessly omitted and concealed known risks. Baldness is caused by a potent male hormone called dihydrotestosterone, or DHT, which is produced in the adrenal glands, hair follicles, testicles and prostate gland. DHT is derived from the male sex hormone, testosterone. The enzyme 5 -reductase converts testosterone to DHT. In people genetically predisposed to male-pattern baldness (androgenic alopecia DHT binds to receptors in hair follicles at the top of the scalp. When the DHT hormone acts on these follicles, they shrink and gradually lose the ability to grow thick and healthy hair. As a result, the persons hairline thins and recedes. Hair follicles on the back and side of the head are genetically resistant to DHT, which explains the common pattern seen in male baldness. Fact, propecia blocks propecia sides the enzyme that converts testosterone to DHT, causing a rapid decline in DHT concentration. Nearly 35 million men in the.S. Suffer from this type of hair loss. Other DHT-induced conditions include enlarged prostate and prostate cancer. Propecia belongs to a class of drugs called 5-alpha-reductase inhibitors, which are used to treat conditions stimulated by DHT. Finasteride, the active ingredient in Propecia, blocks the enzyme that converts testosterone to DHT and causes a rapid decline in DHT concentration. Propecia comes in the form of a tan, octagonal, film-coated tablet with a P logo on one side and propecia embossed on the other. The drugs label instructs users to take one 1 mg tablet once daily. Men can take Propecia with or without meals. Within 24 hours of taking Propecia, the concentration of DHT drops by 65 percent. The full effects of daily Propecia use can take three months or more to appear. Stopping treatment leads to reversal of effect within 12 months, according to the drugs label. The most frequently reported adverse reactions to Propecia affect mens propecia sides sexual health. Although no clear causal links between Propecia use and sexual side effects have been established, finasteride suppresses the bodys level of DHT, which plays a major role in sexuality and sexual development, making the connection highly plausible. An FDA analysis of adverse event data revealed a wide range of sexual side effects in otherwise healthy Propecia users ages 21. These problems persisted for an average of 40 months after the men ceased treatment.
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